endocarditis case presentation ppt
Courses in Therapeutics and Disease State Management. Here, we report a case of a patient with a known history of IVDU who presented with clinical symptoms concerning for right- as well as left-sided endocarditis. These symptoms may mean the infection is getting worse: There is a problem with Jeff Elhai, BBSI participants, faculty and staff ENDOCARDITIS/PERICARDITIS Acquired Inflammatory Diseases of the Heart. History (3) Symptoms of heart failure Endocarditis, Meningitis, and Bloodstream Infections. DEBORAH PIERCE, MD, MPH, BETHANY C. CALKINS, MD, AND KRISTEN THORNTON, MD. 65, no. Accessed May 6, 2022. During the current admission, the patients Glasgow coma scale was 13 on presentation. Due to the slow velocity of shunt flow, ASD has a negligible risk for infective endocarditis (IE). Disclaimer: These citations have been automatically generated based on the information we have and it may not be 100% accurate. F. Seghatol and I. Grinberg, Left-sided endocarditis in intravenous drug users: a case report and review of the literature, Echocardiography, vol. Accessed May 6, 2022. 41 Notably, PVE is by itself associated to substantial mortality rates, around 20-33%, which are exacerbated by . However, bacteria on the skin or in the mouth, throat or gut (intestines) may enter the bloodstream and cause endocarditis under the right circumstances. 202.66.172.235 The final result was amazing, and I highly recommend www.HelpWriting.net to anyone in the same mindset as me. According to ESC guidelines, cardiac surgery was indicated in 2,160 (69.3%) patients, but ultimately performed in only 1,596 (73.9%) of them. https://www.uptodate.com/contents/search. RHEUMATISM Definition: The rheumatism (a Rheumatic fever) is systemic, immune, aseptic inflammatory disease - exam you note signs of congestive heart failure: Her skin is cool and she is anxious. (expert opinion). Accessed May 6, 2022. 2, no. Infective endocarditis (IE) is an infection of the endocardial surface of the heart. Heart valves and infective endocarditis. Terms of Use 19, no. To the best of our knowledge, only five previous cases have been reported where patients with IVDU had bilateral cardiac IE. BAV nuevo Endocarditis and Other Intravascular Infections. Clinical history consistent with infectious endocarditis includes the combination of a prior cardiac lesion and evidence of a recent source of bacteremia. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. debris organisms. Internal Medicine Lecture Series Introduction Background Defined as an infection of the endocardial surface of the heart, which may | PowerPoint PPT presentation | free to view. . In endocarditis, irregular growths made of germs and cell pieces form a mass in the heart. Common blood culture isolates include Staphylococcus aureus, viridans Streptococcus, enterococci, and coagulase-negative staphylococci. Sokumbi O. Instant access to millions of ebooks, audiobooks, magazines, podcasts and more. 63, no. Treatments for endocarditis include medications and surgery. Hematuria. E. Ruotsalainen, K. Sammalkorpi, J. Laine et al., Clinical manifestations and outcome in Staphylococcus aureus endocarditis among injection drug users and nonaddicts: a prospective study of 74 patients, BMC Infectious Diseases, vol. Endocarditis is usually caused by an infection with bacteria, fungi or other germs. Presenting vital signs included a blood pressure of 140/79mm Hg, temperature of 36.4 Celsius, heart rate of 114 beats per minute, respiratory rate of 28 breaths per minute, and oxygen saturation of 95% on 3 liters of supplemental oxygen. You're at high risk of endocarditis and need antibiotics before dental work if you have: If you have endocarditis or any type of congenital heart disease, talk to your dentist and other care providers about your risks and whether you need preventive antibiotics. Activate your 30 day free trialto continue reading. The present case illustrates an unusual evolution of infective endocarditis and highlights the need for a carefully considered approach, based not only on the guidelines but also on assessment of the risks and benefits of surgical intervention, taking into account the patient's characteristics, clinical course, laboratory results and imaging The upper chambers the right and left atria receive incoming blood. 17, pp. Free access to premium services like Tuneln, Mubi and more. cardiac tissue. A. Mgge, W. G. Daniel, G. Frank, and P. R. Lichtlen, Echocardiography in infective endocarditis: reassessment of prognostic implications of vegetation size determined by the transthoracic and the transesophageal approach, Journal of the American College of Cardiology, vol. Enjoy access to millions of ebooks, audiobooks, magazines, and more from Scribd. 58, pp. 102, no. Risk factors include the presence of a prosthetic heart valve, structural or congenital heart disease, intravenous drug use, and a recent history of invasive procedures. Sun LC, Lai CC, Wang CY, et al. Successful treatment requires appropriate antibiotic therapy. A 56-year-old male presented with a 3-day history of altered mental status and weakness. Staphylococcus aureus is the most common causative microorganism [2, 3]. Infective endocarditis (IE) is an infection of the endocardium and/or heart valves that involves thrombus formation (vegetation), which may damage the endocardial tissue and/or valves. 1, 137 pages, 2006. G. Habib, P. Lancellotti, and B. Iung, 2015 ESC guidelines on the management of infective endocarditis: a big step forward for an old disease, Heart, vol. Case presentation. This is an open access article distributed under the, https://www-ncbi-nlm-nih-gov.proxy.kumc.edu/pmc/articles/PMC1767660/pdf/hrt08900577.pdf. Its intracardiac effects include severe valvular insufficiency, which may lead to intractable congestive heart failure and myocardial abscesses. Weve updated our privacy policy so that we are compliant with changing global privacy regulations and to provide you with insight into the limited ways in which we use your data. There are only 15 reported cases in the literature of mitral prosthetic valve bacterial endocarditis causing stenosis by obstruction. 2018; doi:10.1007/s11886-018-1043-2. Talha AM, et al. Enjoy access to millions of ebooks, audiobooks, magazines, and more from Scribd. We present a case of IVSA presenting with a new-onset second-degree heart block, which rapidly progressed to a complete heart block. privacy practices. information and will only use or disclose that information as set forth in our notice of A typical heart has two upper and two lower chambers. Open Forum Infectious Diseases. Overdiagnosis and underdiagnosis of infectious endocarditis can be problematic; a missed diagnosis could prove fatal, whereas overdiagnosis can result in weeks of unnecessary antibiotic treatment. Title: Infective Endocarditis Author: Thomas Hawn Last modified by: thdellit Created Date: 12/19/2001 7:32:20 PM Document presentation format: On-screen Show, Title: 1 ( ) Author: IgraY Last modified by: nivz Created Date: 10/19/2003 10:38:06 AM Document presentation format: On-screen Show. Looks like youve clipped this slide to already. An 81-year-old Middle Eastern male patient with unremarkable medical family history and with DM, hypertension, and multinodular goiter as past medical history was admitted to our hospital three times over a period of 2 months for fever and cough (Table (Table1). Infective endocarditis: Update on epidemiology, outcomes, and management. Among these cases, left-sided manifestations included paravalvular abscess with aortico-left atrial fistula [13], isolated mitral valve vegetations [14], aortic and mitral valve vegetations [15], extension of tricuspid vegetation through patent foramen ovale [16], and vegetation in the left ventricular outflow tract and mitral valve found on autopsy [17]. Fewer than one-half of persons with infectious endocarditis who use injection drugs have evidence of a structural or congenital valvular lesion, with estimates between 6 and 40 percent. Flu-like symptoms, such as fever and chills, A new or changed whooshing sound in the heart (murmur), Tenderness under the left rib cage (spleen), Painless red, purple or brown flat spots on the soles bottom of the feet or the palms of the hands (Janeway lesions), Painful red or purple bumps or patches of darkened skin (hyperpigmented) on the tips of the fingers or toes (Osler nodes), Tiny purple, red or brown round spots on the skin (petechiae), in the whites of the eyes or inside the mouth, Pockets of collected pus (abscesses) that develop in the heart, brain, lungs and other organs, Blood clot in a lung artery (pulmonary embolism), Certain types of congenital heart disease, Congenital heart disease surgery in the last six months. Embolic events occurred in 20.6% of patients, and were significantly associated with tricuspid or pulmonary IE, documented presence of a vegetation, and Staphylococcus aureus IE. Prosthetic valve endocarditis represents 20% of all cases of IE, and its incidence is increasing over time 40; stroke is a frequent presentation occurring in 30% of the patients with a valve prosthesis previously implanted. information is beneficial, we may combine your email and website usage information with health information, we will treat all of that information as protected health Aniket S. Rali and Mejalli Al-Kofahi contributed equally to the manuscript. L. M. Baddour, W. R. Wilson, A. S. Bayer et al., Infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications, Circulation, vol. Antibiotic treatment of infectious endocarditis depends on whether the involved valve is native or prosthetic, as well as the causative microorganism and its antibiotic susceptibilities. Classically, IVDU has been thought to be the main cause of right-sided valvular IE. Tap here to review the details. The authors declare that there is no conflict of interest regarding the publication of this article. Cultivos -, sin fiebre y estable despu s de 24 hrs de antibi ticos suspected, but after susceptibility data are available, therapy demonstrated susceptibility to the drug. Mayo Clinic. 787789, 2009. Check with your local chapter or print the card from the association's website. ?? Atrial fib may occur. Click here to review the details. McGraw Hill, . Creatine kinase was 1288U/L (35232U/L), lactic acid was 3.1mmol/L (0.52.0mmol/L), and troponin was 0.18ng/mL (00.05ng/mL). We've updated our privacy policy. A case of infective endocarditis By Dr P. Arul M4, Prof P. Vijayaraghavan's unit. Risk factors for infective endocarditis in children with congenital heart diseases - A nationwide population-based case control study. - Treated as gouty arthritis but in vain. The ease of this test makes it the obvious choice for initial evaluation. Cultivos -, sin fiebre y estable despu s de 24 hrs de antibi ticos Bacteremia and Endocarditis: Products and Guidance. If you've been diagnosed with endocarditis and have any of the following symptoms, tell your care provider. Case Report A 56-year-old male presented with a 3-day history of altered mental status and weakness. F. A. Dressler and W. C. Roberts, Infective endocarditis in opiate addicts: analysis of 80 cases studied at necropsy, The American Journal of Cardiology, vol. TEE has greater than 90% sensitivity for native valve vegetation and 90% sensitivity for paravalvular abscess. https://www.ada.org/en/member-center/oral-health-topics/antibiotic-prophylaxis. 6, no. Of 5,001 patients identified in the survey, 159 patients had active IE (74% NVE, 26% PVIE); a previous publication described those patients and their outcomes (Tornos P, et al., Heart 2005;91:571-5). A prospective, randomized clinical trial noted a higher incidence of right-sided lesions with IVDU. What risk factors for IE does E.F. have? Definition : Infective endocarditis is characterized by colonization or invasion of the heart valves or the mural endocardium by a microbe, leading to the formation of bulky friable vegetations composed of thromb and organisms, often associated with destruction of the underlying cardiac tissues. This lining is called the endocardium. The incidence of endocarditis is approximately 5 to 7.9 cases per 100,000 persons per year in the United States,1 and has been stable over time. In addition, we also discuss what should be considered adequate evaluation for patients with suspected endocarditis, and more specifically, what should be the role of transesophageal echocardiography in patients with IE noted on transthoracic echocardiography. This div only appears when the trigger link is hovered over. Title: ENDOCARDITIS INFECCIOSA Author: CARLOS ZAPATEL Last modified by: data Created Date: 9/2/2006 1:42:27 AM Document presentation format: Presentaci n en pantalla Infective Endocarditis Prof DR Asem Shehabi Faculty of medicine, University of Jordan Infective endocarditis-1 Fever of unknown origin (FUO) is caused by a wide infective endocarditis Infective endocarditis IE Infective endocarditis IE INFECTIVE ENDOCARDITIS Vegetations (arrows) due to viridans streptococcal endocarditis involving the mitral valve. All of the patients had positive Staphylococcus aureus bacteremia [1316], except one who had negative blood cultures but vegetations with gram positive cocci on autopsy [17]. Preexisting structural abnormalities of the heart are present in 75 percent of patients with infectious endocarditis.5 Historically, rheumatic heart disease was the most common cardiac abnormality in infectious endocarditis6; however, degenerative lesions such as mitral valve prolapse are becoming an increasingly prevalent cause.5 Aortic valve disease and congenital heart disease in the setting of bacteremia are also common risk factors. Free access to premium services like Tuneln, Mubi and more. The valves have a particularly high propensity for infection due to the lack of blood supply and limited access to immune cells. - ALCALOSIS METAB LICA RESIDENCIA DE CL NICA Juan Manuel L pez 2011 Tratamiento: 1) Abandonar diur ticos si es posible. Mayo Clinic is a not-for-profit organization. Endocarditis Jim Czarnecki, D.O. Accessibility Advertising revenue supports our not-for-profit mission. The SlideShare family just got bigger. Extended intravenous drug use (IVDU) is a known risk factor for infective endocarditis (IE) [1]. Group three presentation. A case of infective Ischemia of an extremity. JAMA 1998; 279:599. Outcomes remain very poor, with in-hospital mortality of 17% for the whole group, 20% for PVIE, 16% for NVE, and 15% for CDRIE. Infective endocarditis. Usually, the body's immune system destroys any harmful bacteria that enter the bloodstream. Current Cardiology Reports. CK-MB may be elevated. The crude incidence of infective endocarditis increased from 1990 to 1995 but has remained relatively static thereafter. "Infective Endocarditis." Infectious Diseases: A Case Study Approach Cho JC. McGraw Hill; 2022. https://accessmedicine.mhmedical.com. Physical examination was limited by the patients inability to cooperate, but the patient was noted to have left lower quadrant abdominal tenderness, bilateral lower extremity and right upper extremity wounds, and a large tender sacrocoxal erythematous ulcerated lesion. Things that make you more likely to get endocarditis are artificial heart valves, damaged heart valves or other heart defects. Vincent LL, et al. Late infection, which occurs at least 12 months after placement of the prosthesis, involves microbes and entry portals similar to those of native valve endocarditis.3 Late prosthetic valve endocarditis can also cause perivalvular invasion and extension into nearby tissue, potentially evolving into myocardial abscess, pericarditis, or conduction system disruption and heart block. 614617, 2004. Microorganisms involved were staphylococci in 1,085 (44.1%) patients, oral streptococci in 304 (12.3%), enterococci in 390 (15.8%), and Streptococcus gallolyticus in 162 (6.6%). | PowerPoint PPT presentation | free to download, - Dr. Sarita Rao is a Sr. interventional cardiologist and Top cardiologist in Indore at Apollo Hospitals for heart disease treatment. Infective endocarditis (IE) is defined as an infection of the endocardial surface of the heart, which may include one or more heart valves, the mural endocardium, or a septal defect. Patients should receive information about daily dental hygiene, regular visits to the dentist, and the need for antibiotic prophylaxis for certain procedures (Table 4).19. By accepting, you agree to the updated privacy policy. A. M. Johri, K. A. Kovacs, and H. Kafka, An unusual case of infective endocarditis: extension of a tricuspid valve vegetation into the left atrium through a patent foramen ovale, The Canadian Journal of Cardiology, vol. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. They can break loose and travel to the brain, lungs, kidneys and other organs. We present 2 cases of acute AR (case 1, infective endocarditis; case 2, Stanford type A aortic dissection), and we propose management plans for each case ( Figure 1 A and 1 B). endocardium by microbes. 2023 American College of Cardiology Foundation. Infective endocarditis. the unsubscribe link in the e-mail. Slide Set | 2020 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease Share via: Print Download PowerPoint File Description: See Also: Guideline Hub | Valvular Heart Disease Date: December 17, 2020 Virginia Commonwealth University. Endocarditis may develop slowly or suddenly. In the heart, they attach to damaged heart valves or damaged heart tissue. The mitral valve had a vegetation on the P3 segment. 155, no. IE is relatively rare in children. https://www.heart.org/en/health-topics/heart-valve-problems-and-disease/heart-valve-problems-and-causes/heart-valves-and-infective-endocarditis. He was admitted to the medical intensive care unit (MICU) for pressor support and mechanical ventilation. Endocarditis should be suspected in patients with unexplained fevers, night sweats, or signs of systemic illness. Older studies reported equal frequencies of right- and left-sided lesions [8]. The current hospitalization was his second within eight months, as he was previously hospitalized for methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia due to cellulitis and osteomyelitis attributed to extensive ongoing intravenous drug injections through lower extremity veins. Chu VH, et al. Definite infective endocarditis = two major, or one major and three minor, or five minor; possible infective endocarditis = one major and one minor, or three minor. BUN. Otherwise the patient has had no major medical issues in the last year since her aortic valve replacement. 15, pp. CK-MB may be elevated. Accessed May 6, 2022. If you are a Mayo Clinic patient, this could In our case, multiple bilateral vegetations leading to pulmonic and systemic septic emboli were noted on TEE, only one of which was diagnosed on initial TTE. Copyright 2023 American Academy of Family Physicians. Infective Endocarditis, - Title: 1 ( ) Author: IgraY Last modified by: nivz Created Date: 10/19/2003 10:38:06 AM Document presentation format: On-screen Show. Make a donation. Staphylococcus aureus The plague is caused Cuatro semanas de fiebre, dolor de p lvico y de espalda, y p rdida de peso. Infective endocarditis (IE) often presents non-specifically, most commonly with fever and symptoms/signs of embolism. Please consult the latest official manual style if you have any questions regarding the format accuracy. Abstract K-1930. In general, anticoagulation should be discontinued for at least the first two weeks of antibiotic therapy in patients with Staphylococcus aureus prosthetic valve endocarditis who have experienced a recent central nervous system embolic event.3. Endocarditis is usually caused by an infection. 2. Uploaded on Aug 21, 2014 Derry Hackett + Follow tissue injury elderly diabetic valvular heart disease kingella peripheral manifestations nonenterococcal group d streptococci Download Presentation INFECTIVE ENDOCARDITIS Mayo Clinic. Endocarditis is usually caused by an infection. Valvular structural and functional integrity may be adversely affected in infectious endocarditis, and surgical consultation is warranted in patients with aggressive or persistent infections, emboli, and valvular compromise or rupture. . By accepting, you agree to the updated privacy policy. Infectious endocarditis results from bacterial or fungal infection of the endocardial surface of the heart and is associated with significant morbidity and mortality. 3949, 2017. Case Study E.F. is a 72-year-old man who comes to the clinic with "ulike" symptoms. Dr. Sarita Rao is a Sr. interventional cardiologist and Top cardiologist in Indore at Apollo Hospitals for heart disease treatment. Prior Kawasaki's or Rheumatic disease without valvular dysfunction - Title: Slide 1 Created Date: 1/15/2008 6:07:26 PM Document presentation format: On-screen Show Company: Dataplow Other titles: Times New Roman Arial Tall Paul Pulse - Title: ENDOCARDITIS INFECCIOSA Author: CARLOS ZAPATEL Last modified by: data Created Date: 9/2/2006 1:42:27 AM Document presentation format: Presentaci n en pantalla - Infective Endocarditis Prof DR Asem Shehabi Faculty of medicine, University of Jordan Infective endocarditis-1 Fever of unknown origin (FUO) is caused by a wide - infective endocarditis Infective endocarditis IE Infective endocarditis IE - INFECTIVE ENDOCARDITIS Vegetations (arrows) due to viridans streptococcal endocarditis involving the mitral valve. TEE is well known to have much greater sensitivity for the detection of infective endocarditis. The patient is a 36-year-old male with bicuspid . 6, pp. This lining is called the endocardium. Baseline electrocardiography should be performed in patients with infectious endocarditis so that new cardiac manifestations can be recognized early (e.g., extension of valvular disease into the conduction system, ischemia secondary to emboli to the coronary circulation).3 If tricuspid valve endocarditis is suspected in persons who use injection drugs, chest radiography may reveal evidence of septic pulmonary emboli. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. Save figures into PowerPoint; Download tables as PDFs; . Accessed May 6, 2022. The Patient. Case report on infective endocarditis It appears that you have an ad-blocker running. Copyright 2012 by the American Academy of Family Physicians. Infective Endocarditis. Pan-computed tomography (CT) scans revealed bilateral multiple pulmonary nodular opacities, some of which were cavitary in nature concerning for multifocal pneumonia, acute hematomas in the abdominal wall musculature, and multiple subacute to chronic left cerebellar and left occipital infarcts, all concerning for septic emboli. Underwood 2004 Unrepaired cyanotic CHD (includes palliative shunts and conduits) Assistant Professor of Medicine. Infective Endocarditis. 429431, 2009. endocarditis J. San Romn, I. Vilacosta, J. Zamorano, C. Almera, and L. Snchez-Harguindey, Transesophageal echocardiography in right-sided endocarditis, Journal of the American College of Cardiology, vol. Privacy Policy Do not sell or share my personal information, 1. They can also travel to the arms and legs. By whitelisting SlideShare on your ad-blocker, you are supporting our community of content creators. See permissionsforcopyrightquestions and/or permission requests. What is the causative agent of acute bacterial endocarditis? 46 year old male presented with c/o Fever 3 weeks duration Slurring of speech 1 day Weakness of left upper and lower limbs 1 day History of present illness: Fever 3 weeks duration Intermittent High grade Not associated with chills, rigors. TEE showed vegetations on the tricuspid, mitral, and aortic valves, as well as in the right ventricular outflow tract. See Also: Table 2 shows the incidence of various microorganisms identified in a long-term multicenter study of infectious endocarditis.2 Table 3 summarizes antibiotic recommendations from the American Heart Association.16, For the purposes of determining duration of therapy, the first day in which negative blood cultures are obtained is considered the first day of therapy. Temporal trends of infective endocarditis in North America from 2000 to 2017 A systematic review. Specificity on both modalities is similar and is greater than 90% [11, 12]. American Dental Association. 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endocarditis case presentation ppt