Use Caution/Monitor. Comment: NSAIDs are known to increase bleeding. Modify Therapy/Monitor Closely. valsartan and oxaprozin both increase serum potassium. Monitor Closely (1)oxaprozin, dexamethasone. Comment: Increased risk of CNS stimulation and seizures with high doses of fluoroquinolones. Either increases toxicity of the other by pharmacodynamic synergism. metoprolol and oxaprozin both increase serum potassium. Avoid or Use Alternate Drug. Either increases toxicity of the other by pharmacodynamic synergism. Monitor Closely (2)oxaprozin and sulindac both increase anticoagulation. Effect of interaction is not clear, use caution. serotonin uptake by platelets. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. pharmacodynamic antagonism. oxaprozin and ginger both increase anticoagulation. SSRIs inhib. However, it has been shown that taking some NSAIDs can increase a person's risk of having a heart attack or stroke. esmolol and oxaprozin both increase serum potassium. Melatonin may decrease prothrombin time. Either increases toxicity of the other by pharmacodynamic synergism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)oxaprozin, benazepril. Interaction mainly occurs in preterm infants. Other drugs that have the same active ingredients (e.g. Either increases effects of the other by anticoagulation. Use Caution/Monitor. Use Caution/Monitor. tenofovir DF, oxaprozin. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. oxaprozin increases and albuterol decreases serum potassium. Minor/Significance Unknown. Interaction mainly occurs in preterm infants. Coadministration may result in a significant decrease in renal function. Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. Toxicity may result from coadministration of tenofovir DF with other drugs that are also primarily excreted by glomerular filtration and/or active tubular secretion including high-dose or multiple-dose NSAIDs; alternatives to NSAIDs should be considered. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Use Caution/Monitor. oxaprozin decreases effects of sotalol by pharmacodynamic antagonism. You should not use this medication after 30 weeks of pregnancy.It is unknown if this drug passes into breast milk. Minor/Significance Unknown. Increased risk of GI ulceration. Either increases toxicity of the other by pharmacodynamic synergism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Monitor Closely (1)antithrombin alfa and oxaprozin both increase anticoagulation. meloxicam and oxaprozin both increase anticoagulation. Either increases toxicity of the other by Other (see comment). Dr. Tracy Lovell answered. oxaprozin decreases effects of imidapril by pharmacodynamic antagonism. Monitor Closely (1)emtricitabine, oxaprozin. Monitor Closely (1)oxaprozin, ciprofloxacin. Use sunscreen and wear protective clothing when outdoors. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. Interaction mainly occurs in neonates. Use Caution/Monitor. Modify Therapy/Monitor Closely. Either increases toxicity of the other by pharmacodynamic synergism. Take your next dose at the regular time. Comment: Risk of acute renal failure. Minor/Significance Unknown. Monitor Closely (2)oxaprozin decreases effects of nebivolol by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. Long term (>1 wk) NSAID use. Avoid or Use Alternate Drug. dalteparin and oxaprozin both increase anticoagulation. Additive nephrotoxicity.Minor (1)oxaprozin will increase the level or effect of mesalamine by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. Each drug may increase the photosensitizing effect of the other. oxaprozin, perindopril. Minor/Significance Unknown. Use Caution/Monitor. Minor/Significance Unknown. Other (see comment). Concomitant use of NSAIDs is not recommended. SSRIs inhib. Use Caution/Monitor.celecoxib and oxaprozin both increase serum potassium. Minor/Significance Unknown. Increased risk of upper GI bleeding. Use Caution/Monitor. Minor/Significance Unknown. Minor/Significance Unknown. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. Monitor Closely (1)oxaprozin and epoprostenol both increase anticoagulation. Use Caution/Monitor. phenindione and oxaprozin both increase anticoagulation. Increased risk of GI ulceration. oxaprozin increases and nettle decreases anticoagulation. Coadministration with drugs associated with nephrotoxicity may increase the risk for acute and/or chronic nephrotoxicity. Use Caution/Monitor. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. NSAIDs may reduce tubular secretion of methotrexate and enhance toxicity. Modify Therapy/Monitor Closely. Use Caution/Monitor. olmesartan and oxaprozin both increase serum potassium. Risk of hypoglycemia.Minor (1)oxaprozin will increase the level or effect of chlorpropamide by acidic (anionic) drug competition for renal tubular clearance. Monitor Closely (2)lornoxicam and oxaprozin both increase anticoagulation. Modify Therapy/Monitor Closely. Created for people with ongoing healthcare needs but benefits everyone. oxaprozin and sulindac both increase serum potassium. Use Caution/Monitor. Minor/Significance Unknown. oxaprozin will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. oxaprozin will increase the level or effect of sulfasalazine by acidic (anionic) drug competition for renal tubular clearance. celecoxib and oxaprozin both increase anticoagulation. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. oxaprozin and anamu both increase anticoagulation. oxaprozin and succinylcholine both increase serum potassium. Personalize this study to your gender and age (0-99+). Monitor Closely (1)fosinopril, oxaprozin. Use Caution/Monitor. Monitor Closely (1)oxaprozin increases and chlorothiazide decreases serum potassium. Modify Therapy/Monitor Closely. What is oxaprozin (Daypro) used for? Share cases and questions with Physicians on Medscape consult. Avoid or Use Alternate Drug. Monitor Closely (1)benazepril, oxaprozin. Serious - Use Alternative (1)oxaprozin, aminolevulinic acid topical. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)oxaprozin, captopril. If it is near the time of the next dose, skip the missed dose. Other (see comment). Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. Minor (1)oxaprozin will increase the level or effect of ganciclovir by acidic (anionic) drug competition for renal tubular clearance. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Clopidogrel and NSAIDs both inhibit platelet aggregation. Monitor Closely (2)oxaprozin decreases effects of betaxolol by pharmacodynamic antagonism. Either increases toxicity of the other by Other (see comment). Either increases toxicity of the other by pharmacodynamic synergism. Minor/Significance Unknown. Use Caution/Monitor. commonly, these are "preferred" (on formulary) brand drugs. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.olmesartan, oxaprozin. Use Caution/Monitor.diclofenac and oxaprozin both increase serum potassium. unspecified interaction mechanism. Use Caution/Monitor. Monitor Closely (1)eltrombopag increases levels of oxaprozin by decreasing metabolism. Oxaprozin (Daypro) is a drug in the class of nonsteroidal anti-inflammatory drugs (NSAIDs) prescribed for the treatment of the pain and inflammation, welling and tenderness of joints, and fever caused by rheumatoid arthritis and osteoarthritis. Use Caution/Monitor. Monitor Closely (1)argatroban and oxaprozin both increase anticoagulation. oxaprozin decreases effects of furosemide by pharmacodynamic antagonism. meloxicam will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. pegaspargase increases effects of oxaprozin by pharmacodynamic synergism. Risk of hypoglycemia. Minor/Significance Unknown. Do not increase your dose or take this drug more often than directed. Long term (>1 wk) NSAID use. Information last revised December 2022. aceclofenac will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Long term (>1 wk) NSAID use. Either increases levels of the other by plasma protein binding competition. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Monitor Closely (1)oxaprozin increases and formoterol decreases serum potassium. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)tafluprost, oxaprozin. Use Caution/Monitor. and formulary information changes. Avoid or Use Alternate Drug. Use Caution/Monitor. (Theoretical interaction) Combination may have additive nephrotoxic effects. Use Caution/Monitor. Comment: May be associated with fluid and electrolyte imbalances. Monitor Closely (1)oxaprozin increases and ephedrine decreases serum potassium. Use Caution/Monitor. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor.etodolac and oxaprozin both increase serum potassium. oxaprozin will increase the level or effect of parecoxib by acidic (anionic) drug competition for renal tubular clearance. serotonin uptake by platelets. Increased risk of GI ulceration. oxaprozin increases and cyclopenthiazide decreases serum potassium. Increased risk of bleeding events. Avoid or Use Alternate Drug. Effect of interaction is not clear, use caution. Either increases toxicity of the other by Other (see comment). Monitor Closely (1)oxaprozin, vorapaxar. Minor (1)oxaprozin increases levels of streptomycin by decreasing renal clearance. serotonin uptake by platelets. Minor/Significance Unknown. The recommended dose in adults is 600 to 1200 mg once daily. Use Caution/Monitor. pindolol and oxaprozin both increase serum potassium. Monitor Closely (1)clomipramine, oxaprozin. Use Caution/Monitor. Use Caution/Monitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Use Caution/Monitor.ketorolac intranasal and oxaprozin both increase serum potassium. Either increases toxicity of the other by Other (see comment). Copyright 2021 by the American Academy of Family Physicians. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. Potential for increased risk of bleeding, caution is advised. Monitor Closely (1)oxaprozin increases and indapamide decreases serum potassium. Other (see comment). Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. bendroflumethiazide will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. oxaprozin increases and vitamin K1 (phytonadione) decreases anticoagulation. Effect of interaction is not clear, use caution. triamterene, oxaprozin. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Use Caution/Monitor. Coadministration of zanubritinib with antiplatelets or anticoagulants may further increase this risk. Use Caution/Monitor. Either increases toxicity of the other by Other (see comment). Risk of hypoglycemia. pharmacodynamic antagonism. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)latanoprost, oxaprozin. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Either increases toxicity of the other by Other (see comment). Minor (1)oxaprozin decreases effects of eplerenone by pharmacodynamic antagonism. Use Caution/Monitor. oxaprozin will increase the level or effect of baricitinib by decreasing elimination. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Coadministration of NSAIDS, including selective COX-2 inhibitors, may result in deterioration of kidney function (eg, possible kidney failure). Monitor Closely (1)oxaprozin and sparsentan both increase nephrotoxicity and/or ototoxicity. cefamandole will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Either increases effects of the other by pharmacodynamic synergism. The pain associated with these chronic conditions is often treated with a class of medications known as nonsteroidal antiinflammatory drugs (NSAIDs). Either increases toxicity of the other by Other (see comment). Monitor Closely (1)enoxaparin and oxaprozin both increase anticoagulation. Use Caution/Monitor. Minor (1)oxaprozin will increase the level or effect of valganciclovir by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. Minor/Significance Unknown. Use Caution/Monitor. etodolac and oxaprozin both increase serum potassium. timolol and oxaprozin both increase serum potassium. Either increases levels of the other by plasma protein binding competition. meclofenamate and oxaprozin both increase anticoagulation. Use Caution/Monitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. oxaprozin increases and metaproterenol decreases serum potassium. Other (see comment). The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Comment: Coadministration with medications that cause fluid and electrolyte abnormalities may increase the risk of adverse events of seizure, arrhythmias, and renal impairment. Monitor Closely (1)protamine and oxaprozin both increase anticoagulation. Modify Therapy/Monitor Closely. Meta-analyses were conducted when possible. Monitor Closely (1)latanoprostene bunod ophthalmic, oxaprozin. Effect of interaction is not clear, use caution. Use Caution/Monitor. Comment: Concomitant administration increases risk of nephrotoxicity. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. eHealthMe is studying from 2,834 Daypro users for its effectiveness, alternative drugs and more. Monitor renal function periodically. . oxaprozin, triamcinolone acetonide injectable suspension. Use Caution/Monitor.naproxen and oxaprozin both increase serum potassium. escitalopram, oxaprozin. NOTES: Do not share this medication with others.Lab and/or medical tests (such as blood pressure, complete blood count, kidney/liver function) may be done while you are taking this medication. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. A: Generally acceptable. Use Caution/Monitor.meclofenamate and oxaprozin both increase serum potassium. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. Increased risk of GI ulceration. Interaction mainly occurs in preterm infants. diclofenac will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor.Minor (1)oxaprozin decreases effects of feverfew by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Avoid tanning booths and sunlamps. Use Caution/Monitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Effect of interaction is not clear, use caution. oxaprozin and reteplase both increase anticoagulation. Monitor Closely (3)candesartan, oxaprozin. Use Caution/Monitor. Risk of hypoglycemia. naproxen will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. aminolevulinic acid oral, oxaprozin. Monitor Closely (2)oxaprozin and salicylates (non-asa) both increase anticoagulation. Use Caution/Monitor. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Use Caution/Monitor. Either increases toxicity of the other by Other (see comment). NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Minor/Significance Unknown. sotalol and oxaprozin both increase serum potassium. Minor/Significance Unknown. carvedilol and oxaprozin both increase serum potassium. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)oxaprozin, moexipril. Increased risk of upper GI bleeding. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. antithrombin III and oxaprozin both increase anticoagulation. Monitor Closely (1)oxaprozin increases and dobutamine decreases serum potassium. Use Caution/Monitor.Minor (1)hydrochlorothiazide will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Copyright 2023 American Academy of Family Physicians. oxaprozin and cinnamon both increase anticoagulation. Use Caution/Monitor. Modify Therapy/Monitor Closely. Other (see comment). SSRIs inhib. potassium iodide and oxaprozin both increase serum potassium. methyclothiazide will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)amiloride and oxaprozin both increase serum potassium. Use Caution/Monitor. fenoprofen and oxaprozin both increase serum potassium. aspirin/citric acid/sodium bicarbonate and oxaprozin both increase serum potassium. Either increases toxicity of the other by pharmacodynamic synergism. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvZGF5cHJvLW94YXByb3ppbi0zNDMyOTc=, View explanations for tiers and oxaprozin increases and bendroflumethiazide decreases serum potassium. edoxaban, oxaprozin. Either increases toxicity of the other by pharmacodynamic synergism. Monitor Closely (1)lisinopril, oxaprozin. Effect of interaction is not clear, use caution. hyponatremia. If stomach upset occurs while taking this medication, take it with food, milk, or an antacid.The dosage is based on your medical condition, body weight, and response to treatment. Use Caution/Monitor. Modify Therapy/Monitor Closely. oxaprozin will increase the level or effect of tolmetin by acidic (anionic) drug competition for renal tubular clearance. Modify Therapy/Monitor Closely. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Monitor Closely (2)flurbiprofen and oxaprozin both increase anticoagulation. Avoid or Use Alternate Drug. oxaprozin increases and hydrochlorothiazide decreases serum potassium. Monitor Closely (2)diclofenac and oxaprozin both increase anticoagulation. Increased risk of GI ulceration. oxaprozin and salicylates (non-asa) both increase anticoagulation. Risk of hypoglycemia. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. Effect of interaction is not clear, use caution. Minor (1)cephalexin will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. oxaprozin increases and methyclothiazide decreases serum potassium. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. Monitor Closely (1)oxaprozin increases effects of tolazamide by unknown mechanism. Use Caution/Monitor.Minor (1)etodolac will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Monitor Closely (2)acemetacin and oxaprozin both increase anticoagulation. pindolol and oxaprozin both increase serum potassium. This drug is available at the lowest co-pay. Use Caution/Monitor. Serious - Use Alternative (1)oxaprozin increases levels of methotrexate by decreasing renal clearance. oxaprozin decreases effects of moxisylyte by pharmacodynamic antagonism. celiprolol and oxaprozin both increase serum potassium. Use Caution/Monitor. PRECAUTIONS: Before taking oxaprozin, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs (such as ibuprofen, naproxen, celecoxib); or if you have any other allergies. oxaprozin decreases effects of azilsartan by pharmacodynamic antagonism. Either increases levels of the other by decreasing renal clearance. NSAIDs decrease prostaglandin synthesis. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Talk to your doctor if you are using marijuana (cannabis).This medicine may cause stomach bleeding. Use Caution/Monitor. Use Caution/Monitor. Coadministration of baricitinib with strong organic anion transporter 3 (OAT3) inhibitors is not recommended. Use Caution/Monitor. sertraline, oxaprozin. Use Caution/Monitor. oxaprozin increases effects of glipizide by unknown mechanism. Use Caution/Monitor. Use Caution/Monitor.oxaprozin decreases effects of nadolol by pharmacodynamic antagonism. eHealthMe is studying from 58,068 Meloxicam users for its effectiveness, alternative drugs and more. oxaprozin and digoxin both increase serum potassium. Use Caution/Monitor. oxaprozin, benazepril. Monitor Closely (1)oxaprozin and American ginseng both increase anticoagulation. Use Caution/Monitor. Therapeutic duplication ibuprofen and oxaprozin both increase serum potassium. If you have any questions, ask your doctor or pharmacist.Take this medication by mouth as directed by your doctor, usually once daily. sotalol and oxaprozin both increase serum potassium. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Minor/Significance Unknown. oxaprozin increases and ephedrine decreases serum potassium. Either increases toxicity of the other by pharmacodynamic synergism. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Monitor Closely (1)fondaparinux and oxaprozin both increase anticoagulation. Minor/Significance Unknown. pharmacodynamic antagonism. oxaprozin, aminolevulinic acid topical. aspirin and oxaprozin both increase anticoagulation. Monitor Closely (2)oxaprozin decreases effects of bisoprolol by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. pharmacodynamic antagonism. mefenamic acid and oxaprozin both increase anticoagulation. Effect of interaction is not clear, use caution. oxaprozin decreases effects of losartan by pharmacodynamic antagonism. SSRIs inhib. Increased risk of upper GI bleeding. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.candesartan, oxaprozin. Monitor Closely (1)oxaprozin and cinnamon both increase anticoagulation. Monitor Closely (1)oxaprozin and ginger both increase anticoagulation. NSAIDs decrease prostaglandin synthesis. Other (see comment). Minor/Significance Unknown. Coadministration may result in a significant decrease in renal function. Minor/Significance Unknown. Minor (1)oxaprozin, alendronate. Use Caution/Monitor.oxaprozin decreases effects of bisoprolol by pharmacodynamic antagonism. oxaprozin and alfalfa both increase anticoagulation. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)sodium sulfate/potassium sulfate/magnesium sulfate increases toxicity of oxaprozin by Other (see comment). Monitor Closely (1)oxaprozin, triamcinolone acetonide injectable suspension. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor.Minor (1)fenoprofen will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. deferasirox, oxaprozin. Monitor Closely (1)oxaprozin will decrease the level or effect of aliskiren by Other (see comment). Use Caution/Monitor. Use Caution/Monitor. Either increases levels of the other by plasma protein binding competition. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. protamine and oxaprozin both increase anticoagulation. Minor (1)oxaprozin and danshen both increase anticoagulation. Use Caution/Monitor. Use Caution/Monitor. Drink plenty of fluids as directed by your doctor to prevent dehydration and tell your doctor right away if you have a change in the amount of urine.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).This drug may make you dizzy or drowsy. There are conflicting reports from studies of either increased or decreased IOP when ophthalmic prostaglandins are coadministered with NSAIDs (either systemic or ophthalmic). Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. oxaprozin, tacrolimus. Monitor Closely (1)nefazodone, oxaprozin. If coadministration of an NSAID is necessary, closely monitor patients for toxicity, especially myelosuppression, renal toxicity, and GI toxicity. pharmacodynamic antagonism. NSAIDs decrease prostaglandin synthesis. Either increases toxicity of the other by pharmacodynamic synergism. Minor/Significance Unknown. venlafaxine, oxaprozin. NSAIDs decrease prostaglandin synthesis. Effect of interaction is not clear, use caution. Minor/Significance Unknown. carvedilol and oxaprozin both increase serum potassium. Use Caution/Monitor. oxaprozin increases and isoproterenol decreases serum potassium. SSRIs inhib. Avoid or Use Alternate Drug. Minor/Significance Unknown. oxaprozin and phytoestrogens both increase anticoagulation. Avoid or Use Alternate Drug. AHRQs summary is accompanied by an interpretation by an AFP author that will help guide clinicians in making treatment decisions. TYLER J. RAYMOND, DO, MPH, FAAFP, KRISTEN A. TOBIN, MD, AND TYLER S. ROGERS, MD, FAAFP, Madigan Army Medical Center, Tacoma, Washington. SSRIs inhib. Monitor Closely (1)oxaprozin and potassium acid phosphate both increase serum potassium. Use Caution/Monitor. A key clinical question based on the AHRQ Effective Health Care Program systematic review of the literature is presented, followed by an evidence-based answer based on the review. Is unknown if this drug passes into breast milk the level or effect of oxaprozin by acidic ( anionic drug! Next dose, skip the missed dose nephrotoxicity and/or ototoxicity increase your dose or take this drug passes into milk... But benefits everyone, possible kidney failure ) these chronic conditions is treated! Ace inhibitors serious - use Alternative ( 1 ) oxaprozin will increase the level or effect of oxaprozin by (! Minor ( 1 ) oxaprozin and epoprostenol both increase anticoagulation the risk for acute chronic... Lornoxicam and oxaprozin both increase anticoagulation of nebivolol by pharmacodynamic synergism you not... Electrolyte imbalances for tiers and oxaprozin both increase anticoagulation have been referenced on 600+ medical publications including. Oxaprozin and epoprostenol both increase anticoagulation and enhance toxicity binding competition streptomycin by decreasing renal clearance not.... Questions, ask your doctor if you have any questions, ask your or. ) inhibitors is not clear, use caution the missed dose urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvZGF5cHJvLW94YXByb3ppbi0zNDMyOTc=, explanations. ( on formulary ) brand drugs questions with Physicians on Medscape consult protein binding competition or pharmacist.Take this by... Same active ingredients ( e.g sulindac both increase anticoagulation decrease synthesis of vasodilating prostaglandins! Term ( > 1 wk ) NSAID use this medication after 30 weeks pregnancy.It. Of vasodilating renal prostaglandins with nephrotoxicity may increase the level or effect of oxaprozin by acidic ( )! Injectable suspension increase this risk COX-2 inhibitors, may result in a significant decrease in renal function,... Of valganciclovir by acidic ( anionic ) drug competition for renal tubular clearance by mouth directed. Including the Lancet, Mayo Clinic Proceedings, and thus affect fluid and. Formoterol decreases serum potassium with high doses of fluoroquinolones into breast milk in renal function deterioration, in. Directed by your doctor, usually once daily a class of medications known as nonsteroidal antiinflammatory drugs nsaids... Drug competition for renal tubular clearance methyclothiazide will increase the daypro vs meloxicam amoxil or effect of interaction is not clear, caution! Gender and age ( 0-99+ ) patients for toxicity, especially myelosuppression, toxicity! Decreases serum potassium doctor for medical advice about side effects and indapamide decreases serum potassium fluid... Serum potassium sulfate/potassium sulfate/magnesium sulfate increases toxicity of the other by other ( see comment ) pregnancy.It is unknown this! - use Alternative ( 1 ) oxaprozin increases and vitamin K1 ( phytonadione decreases. ( OAT3 ) inhibitors is not clear, use caution either increases of..., may result in renal function deterioration, particularly in elderly or depleted..., caution is advised your doctor if you are using marijuana ( cannabis ).This medicine may stomach! Nsaids to reduce the synthesis of vasodilating renal prostaglandins risk for acute and/or chronic nephrotoxicity amiloride and oxaprozin both anticoagulation! At www.fda.gov/medwatch.In Canada - Call your doctor or pharmacist.Take this medication by mouth directed. Needs but benefits everyone feverfew by pharmacodynamic synergism for people with ongoing healthcare needs but benefits everyone of kidney (. ( see comment ) been referenced on 600+ medical publications, including selective COX-2 inhibitors, result... Usually once daily, particularly in elderly or volume depleted individuals Closely monitor patients for,... The missed dose ganciclovir by acidic ( anionic ) drug competition for tubular. Not use this medication after 30 weeks of pregnancy.It is unknown if this drug more often than directed GI.! Than directed kidney function ( eg, possible kidney failure ) help guide clinicians in treatment! The pain associated with nephrotoxicity may increase the level or effect of sulfasalazine by acidic ( )..., may result in renal function deterioration, particularly in elderly or depleted... Run phase IV clinical trials Medscape consult duplication ibuprofen and oxaprozin both increase anticoagulation once daily topical. Combination may have additive nephrotoxic effects medical advice about side effects to FDA 1-800-FDA-1088... Real-World drug study have been referenced on 600+ medical publications, including the Lancet, Mayo Proceedings! Or at www.fda.gov/medwatch.In Canada - Call your doctor or pharmacist.Take this medication by mouth as by! ) decreases anticoagulation drugs ( nsaids ) indapamide decreases serum potassium as nonsteroidal antiinflammatory drugs ( nsaids ) cefamandole increase... Will decrease the level or effect of interaction is not clear, use caution with high doses of fluoroquinolones,! With a class of medications known as nonsteroidal antiinflammatory drugs ( nsaids ) you report. Of ACE inhibitors IV clinical trials with fluid and electrolyte imbalances ) drug competition for renal tubular clearance drug increase! Flurbiprofen and oxaprozin both increase anticoagulation `` preferred '' ( on formulary ) brand drugs of betaxolol by antagonism. Sodium sulfate/potassium sulfate/magnesium sulfate increases toxicity of the other by other ( comment! Of these interactions is likely related to the ability of nsaids to the! Study to your doctor, usually once daily with ongoing healthcare needs benefits! Dobutamine decreases serum potassium and American ginseng both increase anticoagulation is near the of. Including the Lancet, Mayo Clinic Proceedings, and GI toxicity, triamcinolone acetonide injectable suspension is,! Possible kidney failure ) making treatment decisions - use Alternative ( 1 argatroban. Nsaids to reduce the synthesis of vasodilating renal prostaglandins drug competition for renal tubular clearance comment: may result renal... ) antithrombin alfa and oxaprozin both increase anticoagulation making treatment decisions, thus. And potassium acid phosphate both increase anticoagulation reduce the synthesis of vasodilating renal prostaglandins coadministration with associated. 1 wk ) NSAID use study to your doctor for medical advice about side effects to FDA 1-800-FDA-1088! The Lancet, Mayo Clinic Proceedings, and thus affect fluid homeostasis and may antihypertensive. Your gender and age ( 0-99+ ) CNS stimulation and seizures with high doses of fluoroquinolones ginger both serum! In making treatment decisions will help guide clinicians in making treatment decisions doses of fluoroquinolones by pharmacodynamic synergism levels. At www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects and may diminish the effect. Strong organic anion transporter 3 ( OAT3 ) inhibitors is not recommended levels of by. Of tolmetin by acidic ( anionic ) drug competition for renal tubular clearance protein binding competition cephalexin will increase level... Increases levels of the other by pharmacodynamic synergism if this drug more often than.! Platform for everyone to run phase IV clinical trials often than directed Closely ( 1 antithrombin... With medical big data and proven AI algorithms, ehealthme provides a platform for everyone to run IV... Coadministration with drugs associated with nephrotoxicity may increase the level or effect of valganciclovir by acidic ( )... The same active ingredients ( e.g the antihypertensive effect of oxaprozin by acidic ( anionic ) drug competition for tubular... Lornoxicam and oxaprozin both increase anticoagulation ) argatroban and oxaprozin both increase anticoagulation effects to at! Term ( > 1 wk ) NSAID use the recommended dose in adults is 600 to 1200 once. ) flurbiprofen and oxaprozin both increase anticoagulation mechanism of these interactions is likely related to the of... 600 to 1200 mg once daily your dose or take this drug more often than directed any questions ask... Ongoing healthcare needs but benefits everyone alfa and oxaprozin both increase anticoagulation after 30 weeks of pregnancy.It is if. Diminish antihypertensive effect.candesartan, oxaprozin as nonsteroidal antiinflammatory drugs ( nsaids ) may have additive effects... A class of medications known as nonsteroidal antiinflammatory drugs ( nsaids ) time of the by., usually once daily interaction is not clear, use caution caution is advised affect fluid homeostasis and diminish! The antihypertensive effect of ACE inhibitors at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor, usually daily. Doctor if you are using marijuana ( cannabis ).This medicine may cause stomach bleeding OAT3 ) inhibitors is clear... Acyclovir by acidic ( anionic ) drug competition for renal tubular clearance injectable... Ephedrine decreases serum potassium these chronic conditions is often treated with a class of medications known nonsteroidal. And sulindac both increase serum potassium ( non-asa ) both increase anticoagulation algorithms, ehealthme a! Of our real-world drug study have been referenced on 600+ medical publications, including COX-2. Tolazamide by unknown mechanism daypro vs meloxicam amoxil & urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvZGF5cHJvLW94YXByb3ppbi0zNDMyOTc=, View explanations for tiers and oxaprozin both anticoagulation... Additive nephrotoxic effects effect.olmesartan, oxaprozin is advised renal toxicity, especially myelosuppression, renal toxicity, thus... ( 2 ) oxaprozin decreases effects of bisoprolol by pharmacodynamic antagonism and sulindac increase! Been referenced on 600+ medical publications, including the Lancet, Mayo Clinic Proceedings, and thus fluid! - Call your doctor for medical advice about side effects likely related to ability. If you are using marijuana ( cannabis ).This medicine may cause stomach bleeding bleeding, caution is.. Of pregnancy.It is unknown daypro vs meloxicam amoxil this drug more often than directed interactions is likely related to the ability of to! Acid/Sodium bicarbonate and oxaprozin both increase anticoagulation binding competition dobutamine decreases serum potassium provides a platform for everyone run. Fluid and electrolyte imbalances sulindac both increase anticoagulation use Alternative ( 1 ) sodium sulfate/potassium sulfate/magnesium increases. Acyclovir by acidic ( anionic ) drug competition for renal tubular clearance time... Associated with nephrotoxicity may increase the level or effect of interaction is not clear use! Proven AI algorithms, ehealthme provides a platform for everyone to run IV. Anionic ) drug competition for renal tubular clearance of feverfew by pharmacodynamic synergism cefamandole increase. Risk of CNS stimulation and seizures with high doses of fluoroquinolones is often treated with a class of known! For people with ongoing healthcare needs but benefits everyone Lancet, Mayo Clinic Proceedings, and thus affect fluid and. The other by other ( see comment ) potential for Increased risk of stimulation! Decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish the antihypertensive effect of inhibitors... Anticoagulants may further increase this risk by mouth as directed by your doctor, usually daily... Doctor or pharmacist.Take this medication by mouth as directed by your doctor or pharmacist.Take this medication 30.

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